Very rare: transient leukopenia, agranulocytosis, pancytopenia, thrombocytopenia or eosinophilia. There have been isolated cases of blood clotting disorders. Allergic reactions: Rare: allergic reactions (eg, urticaria, pruritus). Very rare: Lyell’s what does deca stand for syndrome (in this case the drug should be discontinued immediately); other allergic reactions associated with sensitization – drug fever, a syndrome resembling serum sickness, hemolytic anemia, interstitial nephritis. With the development of anaphylactic shock administered epinephrine, systemic corticosteroids and antihistamines. Nervous system: Uncommon: headache, dizziness, dysphoria. The reactions of the digestive system: Common: . Abdominal pain, dyspepsia, nausea, vomiting and diarrhea Very rare : pseudomembranous colitis. On the part of the hepatobiliary system: rare: . increased alkaline phosphatase and transaminases Very rare: isolated cases of hepatitis and cholestatic jaundice. From the urogenital system: very rare: a slight increase in the concentration of creatinine in the blood, hematuria.
When taken in doses exceeding the maximum daily, may increase the frequency of dose-related side effects described above. Treatment: gastric lavage; symptomatic and supportive therapy. Hemodialysis and peritoneal dialysis are not effective.
Interaction with other drugs
blockers tubular secretion slow down the excretion of cefixime via the kidneys, which can cause symptoms of overdose.
Cefixime reduces prothrombin index, increases the effects of anticoagulants.
Simultaneous use of cefixime what does deca stand for with carbamazepine was observed increase in the concentration of the latter in plasma; in such cases it is expedient to therapeutic drug monitoring.
In connection with the possibility of a cross-allergic reactions to penicillin, it is advisable to carefully assess the medical history of patients. If you have an allergic reaction, use of the drug should be discontinued immediately.
Chronic administration of the drug may be in breach of the normal intestinal microflora, which can lead to excessive proliferation of Clostridium difficile and the development of pseudomembranous colitis.When a mild antibiotic-associated diarrhea, as a rule, stop taking the drug enough. In more severe forms of corrective treatment is recommended (for example, inside designation vancomycin 250 mg four times a day). Antidiarrheal drugs that inhibit the motility of the gastrointestinal tract, the development of pseudomembranous colitis are contraindicated.
In the case of the drug Tseforal Soljutab simultaneously with aminoglycosides, polymyxin B, sodium kolistimetatom, “loop” diuretics (furosemide, ethacrynic acid) at high doses is necessary to carefully monitor renal function. After what does deca stand for prolonged treatment with Tseforal Soljutab should check the status of hematopoietic function.
Dispersible tablets should be dissolved only in water. During treatment possible false-positive direct Coombs’ test and false positive reaction of urine for glucose with some test systems for rapid diagnosis.
Effects on ability to drive and use machines
Studies of the drug exposure Tseforal Soljutab on ability to drive and use machinery has not been. In connection with the possible adverse effects (eg, dizziness), caution should be exercised.